Health / Medical Topics |
Carzelesin
Pronunciation
Definition 1
An anticancer drug that belongs to the family of drugs called alkylating agents. (NCI Dictionary)
Definition 2
A cyclopropylpyrroloindole prodrug analogue and DNA minor groove binding agent, with antineoplastic activity. After hydrolysis, the cyclopropyl group of carzelesin alkylates N3-adenine in a sequence-selective fashion. This results in tumor growth inhibition. (NCI Thesaurus)
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