Health / Medical Topics

    CASC5 wt Allele

    Human CASC5 wild-type allele is located in the vicinity of 15q14 and is approximately 70 kb in length. This allele, which encodes protein CASC5, is involved in both signaling in mitosis and chromosome alignment. The gene is involved in a translocation t(11;15)(q23;q14) with the MLL gene that is associated with acute myeloblastic leukemia. (NCI Thesaurus)




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