Health / Medical Topics |
CASP3 wt Allele
Human CASP3 wild-type allele is located within 4q34 and is approximately 22 kb in length. This allele, which encodes caspase-3 protein, is involved in the activation of caspase-dependent apoptosis via proteolytic cleavage of poly (ADP-ribose) polymerase as well as caspases 6, 7 and 9. (NCI Thesaurus)
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