CASP7 wt Allele

Human CASP7 wild-type allele is located within 10q25 and is approximately 52 kb in length. This allele, which encodes caspase-7 protein, is involved in apoptosis via the cleavage and activation of both sterol regulatory element binding proteins and poly (ADP-ribose) polymerase (PARP). Overexpression of the CASP7 gene promotes programmed cell death. Loss of heterozygosity of the CASP7 gene has been detected in several types of solid tumors. (NCI Thesaurus)

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CASP7 Gene

This gene plays a role in the execution phase of apoptosis and is also involved in the regulation of lipogenic and cholesterogenic…

CASP6 wt Allele

Human CASP6 wild-type allele is located within 4q25 and is approximately 15 kb in length. This allele, which encodes caspase-6 protein, plays…

CASP6 Gene

This gene is involved in the execution of apoptosis.

CASP5 wt Allele

Human CASP5 wild-type allele is located within 11q22.2-q22.3 and is approximately 15 kb in length. This allele, which encodes caspase-5 protein, is…

CASP5 Gene

This gene plays a role in apoptosis, cell growth and differentiation.

CASP4 wt Allele

Human CASP4 wild-type allele is located within 11q22.2-q22.3 and is approximately 27 kb in length. This allele, which encodes caspase-4 protein, plays…