Health / Medical Topics

    CBFA2T2 wt Allele

    Human CBFA2T2 wild-type allele is located in the vicinity of 20q11 and is approximately 160 kb in length. This allele, which encodes protein CBFA2T2, may play a role in tumor suppression. This gene is frequently fused to RUNX1 by the t(8;21)(q22;q22) translocation in acute myeloid leukemia. (NCI Thesaurus)




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