Health / Medical Topics |
CBLB Gene
This gene plays a role in the regulation of T cell activation. (NCI Thesaurus)
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Human CBL wild-type allele is located in the vicinity of 11q23.3 and is approximately 102 kb in length. This allele, which encodes…
The cellular homologue of v-cbl, CBL protein is expressed in a range of hemopoietic lineages. Malignancies are associated with translocations of…
This gene plays a role in signal transduction and the regulation of protein degradation.
A fusion protein encoded by the CBFB/MYH11 fusion gene. This protein is comprised of most of the core-binding factor subunit beta fused…
A fusion gene that results from a chromosomal inversion inv(16)(p13q22) which fuses the 5' portion of the CBFB gene with the 3'…
Expression of a fusion protein that results from an inversion or translocation, which involves the human genes CBFB and MYH11 and is…