Health / Medical Topics

    CBLB Gene

    This gene plays a role in the regulation of T cell activation. (NCI Thesaurus)




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    Human CBL wild-type allele is located in the vicinity of 11q23.3 and is approximately 102 kb in length. This allele, which encodes…
    The cellular homologue of v-cbl, CBL protein is expressed in a range of hemopoietic lineages. Malignancies are associated with translocations of…
    This gene plays a role in signal transduction and the regulation of protein degradation.
    A fusion protein encoded by the CBFB/MYH11 fusion gene. This protein is comprised of most of the core-binding factor subunit beta fused…
    A fusion gene that results from a chromosomal inversion inv(16)(p13q22) which fuses the 5' portion of the CBFB gene with the 3'…
    Expression of a fusion protein that results from an inversion or translocation, which involves the human genes CBFB and MYH11 and is…

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