cCLB8

A chimeric (made from human and mouse proteins) monoclonal antibody being studied in the treatment of advanced kidney cancer and other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. cCLB8 works by blocking inflammation and tumor growth. Also called anti-IL-6 chimeric monoclonal antibody and CNTO 328. (NCI Dictionary)

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CCL8 wt Allele

Human CCCL8 wild-type allele is located within 17q11.2 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine…

CCL8 Gene

This gene is involved in the modulation of immune functions.

CCL7 wt Allele

Human CCL7 wild-type allele is located within 17q11.2-q12 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine…

CCL7 Gene

This gene plays a role in extracellular matrix modulation and inflammatory processes.

CCL5 wt Allele

Human CCL5 wild-type allele is located within 17q11.2-q12 and is approximately 36 kb in length. This allele, which encodes small inducible cytokine…

CCL5 Gene

This gene plays a role in antiviral responses.