Health / Medical Topics |
CCND2 wt Allele
Human CCND2 wild-type allele is located within12p13 and is approximately 32 kb in length. This allele, which encodes G1/S-specific cyclin D2 protein, plays a role in cell cycle regulation. Methylation of the gene generates allelic variants that are implicated in the pathogenesis of several cancers. (NCI Thesaurus)
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This gene is involved in the regulation of the G1/S phase of the cell cycle.
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