CCR5 wt Allele

Human CCR5 wild-type allele is located within 3p21 and is approximately 6 kb in length. This allele, which encodes C-C chemokine receptor type 5 protein, plays a role in monocyte chemotaxis and G protein-coupled signal transduction. Defective alleles of this gene are associated with HIV infection resistance. (NCI Thesaurus)

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CCR5 Signaling Pathway

The chemokine receptors CCR5 and CXCR4 in macrophages are activated by their peptide ligands and also by the HIV envelope protein GP120…

CCR5 Gene

This gene is involved in G protein-coupled signal transduction and chemotaxis.

CCR4-NOT Transcription Complex Subunit 3

CCR4-NOT transcription complex subunit 3 (753 aa, ~82 kDa) is encoded by the human CNOT3 gene. This protein is involved in transcriptional…

CCR3 Signaling Pathway

Eosinophils are a key class of leukocytes involved in inflammatory responses, including allergic reactions in skin and airway. The eosinophil response…

CCR2 wt Allele

Human CCR2 wild-type allele is located in the vicinity of 3p21.31 and is approximately 7 kb in length. This allele, which encodes…

CCR2 Gene

This gene plays a role in chemokine signaling.