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    CD22 Immunotoxin

    Definition 1

    An immunotoxin composed of an anti-CD22 monoclonal antibody and a toxin moiety, which targets antigen-positive cells and causes cytotoxic activity. (NCI Thesaurus)

    Definition 2

    A monoclonal antibody linked to a toxic substance. It is being studied in the treatment of some types of B-cell cancer. Anti-CD22 immunotoxin is made in the laboratory. It binds to CD22, a protein on the surface of normal B cells and B-cell tumors, and kills the cells. (NCI Dictionary)




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