Health / Medical Topics |
CD3D wt Allele
Human CD3D wild-type allele is located within 11q23 and is approximately 4 kb in length. This allele, which encodes T-cell surface glycoprotein CD3 delta chain protein, plays a role in the regulation of signal transduction underlying the developmental transition of immature thymocytes to mature CD4+ or CD8+ T cells. Certain allelic variants of the CD3D gene cause a form of severe combined immunodeficiency (SCID) characterized by the absence of T cells but normal numbers of B cells and NK cells. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in immunity/defense via the activation of T cells.
Human CD38 wild-type allele is located in the vicinity of 4p15 and is approximately 71 kb in length. This allele, which encodes…
This gene is involved in both signal transduction and the metabolism of ADP-ribose.
The determination of the amount of CD38 expressing cells per unit present in a sample.
Human CD37 wild-type allele is located in the vicinity of 19q13.3 and is approximately 5 kb in length. This allele, which encodes…
This gene is involved in the regulation of immunoglobulin production.