Health / Medical Topics

    CD74 wt Allele

    Human CD74 wild-type allele is located in the vicinity of 5q32 and is approximately 11 kb in length. This allele, which encodes HLA class II histocompatibility antigen gamma chain protein, is involved in MHC class II antigen processing and presentation. A translocation of this gene and the ROS1 gene may be associated with non-small cell lung cancer. (NCI Thesaurus)




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