CDKN1C wt Allele

Human CDKN1C wild-type allele located in the vicinity of 11p15.5 and is approximately 2 kb in length. This allele, which encodes cyclin-dependent kinase inhibitor 1C protein, plays a negative role in the regulation of cellular proliferation by inhibiting several G1 cyclin/Cdk complexes. Mutations of the gene, which generates variant alleles have been implicated in both sporadic cancers and Beckwith-Wiedemann syndrome, suggesting that it is a tumor suppressor candidate. (NCI Thesaurus)

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CDKN1C Gene

This gene plays a regulatory role in the cell cycle.

CDKN1B wt Allele

Human CDKN1B wild-type allele is located within 12p13.1-p12 and is approximately 5 kb in length. This allele, which encodes cyclin-dependent kinase inhibitor…

CDKN1B Gene

This gene is involved in cell cycle regulation and cyclin regulation.

CDKN1A wt Allele

Human CDKN1A wild-type allele is located in the vicinity of 6p21.2 and is approximately 9 kb in length. This allele, which encodes…

CDKN1A Gene

This gene is a regulator of cell cycle progression at the G1 phase of the cell cycle.

CDKL5 wt Allele

Human CDKL5 wild-type allele is located in the vicinity of Xp22 and is approximately 228 kb in length. This allele, which encodes…