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Chemical Interference
A type of footprinting technique used to define the location of protein-nucleic acid contacts at the base pair level in nucleic acids. It utilizes nucleic acids treated with a chemical in such a way that only a fraction of the nucleotides are chemically modified. The chemically modified nucleotides that interfere with protein-nucleic acid complex formation can be identified by fragmentation and electrophoretic analysis of the DNA isolated from the complexes. (NCI Thesaurus)
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Methods of fractionation, isolation, and purification based on the physico-chemical properties of the substance, e.g. crystallization, distillation, solubility (miscibility).
A representation of a substance using symbols for its constituent elements.
Chemical Engineering; engineering dealing with the industrial application of chemistry. (WWWebster Dictionary)
