CHFR wt Allele

Human CHFR wild-type allele is located in the vicinity of 12q24.33 and is approximately 47 kb in length. This allele, which encodes E3 ubiquitin-protein ligase CHFR protein, plays a role in the regulation of mitosis. Mutation or silencing of the gene is associated with multiple cancers. (NCI Thesaurus)

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