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CHIC2/ETV6 Fusion Protein
A fusion protein encoded by the CHIC2/ETV6 fusion gene. This protein is comprised of approximately 110 N-terminal amino acids from the cysteine-rich hydrophobic domain 2 protein fused to the C-terminal half of the transcription factor ETV6 protein, including the helix-loop-helix and ETS DNA-binding domains. (NCI Thesaurus)
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A fusion gene that results from a chromosomal translocation t(4;12)(q11-q21;p13) which fuses exons 1-3 of the CHIC2 gene to exons 2-8 of…
Human CHIC2 wild-type allele is located in the vicinity of 4q11 and is approximately 55 kb in length. This allele, which encodes…
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Chiari malformations (CMs) are structural defects in the cerebellum. The cerebellum is the part of the brain that controls balance. With…
