Health / Health News

    Childhood mental health problems resulting from early-life adversity drive poorer cognitive performance in adolescence

    Early-life adversity – such as poverty, illness or family conflict – has long been linked to mental health difficulties and poorer cognitive functioning as children grow up. But how these factors interact and evolve over time has so far been unknown.



    Childhood mental health problems resulting from early-life adversity drive poorer cognitive performance in adolescence. Photo: Lucas Metz/Unsplash


    Now, a new study by researchers at the University of Cambridge, together with colleagues in Nigeria, has revealed the interplay between early-life adversity, mental health difficulties and cognitive functioning over the course of childhood.

    The results show that childhood mental health influences the extent to which early-life adversity impacts on later cognitive functioning.

    Scientists analysed data from the ongoing Millennium Cohort Study, which has assessed 13,287 children on a variety of tests at ages three, five, seven, eleven and fourteen.

    They selected measures of early-life adversity (which they classified as taking place before the age of three), mental health and cognitive functioning – namely, working memory and vocabulary.

    The team from the MRC Cognition and Brain Sciences Unit, University of Cambridge used a statistical technique designed to tease out the extent to which mental health affects the relationship between early-life adversity and cognitive functioning later in childhood.

    They found that early-life adversity is associated with poorer performance on working memory and vocabulary through its impact on mental health across childhood.

    For example, poorer mental health across ages 3-14 resulting from early-life adversity accounted for 59% of the variance in poorer working memory performance at age 11 and explained 70% of poorer performance in vocabulary at age 14.

    The researchers showed that early-life adversity at age three strongly predicted poorer mental health across ages 3-14, with the association strongest at three but getting progressively weaker over time.

    In other words, children who experienced early-life adversity were most likely to experience mental health difficulties from age three to age fourteen, although poorer mental health was greater at age 3 than in the later years.

    This suggests that exposure to early-life adversity at this developmentally sensitive time has a negative long-term impact on mental health.

    They also found that decreases in mental health difficulties over time were associated with improvements in working memory and vocabulary.

    This suggests that if behavioural and psychological difficulties can be addressed when children are young, the effects of early-life adversity on later cognition could be alleviated.

    This finding has important implications for clinicians, educators and parents involved in interventions.

    “Our findings suggest that early-life adversity can lead to prolonged periods of poor mental health, which in turn may have lasting effects on cognitive performance, such as working memory and vocabulary,” said lead author Dr Tochukwu Nweze from the MRC Cognition and Brain Sciences Unit.

    “We already know that poor mental health and cognition are associated with numerous behavioural problems which affect life quality and satisfaction. This reinforces the need for early interventions to give children the best possible life-outcomes.” (University of Cambridge)

    FEBRUARY 22, 2023



    YOU MAY ALSO LIKE

    NIH researchers discover a possible cause for a rare facial malformation, bringing new hope for patients.
    Scientists at the Department of Energy’s Oak Ridge National Laboratory explored the genetic basis of varicose veins. The team identified 139 locations across the human genome tied to risk factors for the disorder that can guide the development of new treatments.
    In a mouse study, researchers have identified a potential non-hormonal contraceptive that men could take shortly before sexual activity and have fertility restored the next day.
    Researchers have found differences in the gut microbiomes of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) compared to healthy controls.
    Cambridge scientists have successfully trialled an artificial pancreas for use by patients living with type 2 diabetes.
    New technique enables automatic detection of placental compartments, oxygen status and structural abnormalities.

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact