| Library / English Dictionary |
CHOLINERGIC
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Releasing or activated by acetylcholine or a related compound
Classified under:
Antonym:
anticholinergic (inhibiting or blocking the action of acetylcholine at a receptor site)
Context examples:
It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.
(Nicotine, NLM, Medical Subject Headings)
Cholinergic Receptor, Muscarinic 4, encoded by the human CHRM4 gene, is a G protein-coupled receptor.
(Muscarinic Acetylcholine Receptor M4, NCI Thesaurus)
The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.
(Muscarinic Acetylcholine Receptor M3, NCI Thesaurus)
It is innervated by cholinergic nerve fibers.
(Eccrine Sweat Gland, NCI Thesaurus)
Evoxac is a type of cholinergic agonist.
(Evoxac, NCI Dictionary)
In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons.
(Brain-Derived Neurotrophic Factor, NLM, Medical Subject Headings)
Furthermore, duloxetine does not show significant affinity for dopaminergic, adrenergic, cholinergic, histaminergic, opioid, glutamate, and gamma-aminobutyric acid (GABA) receptors.
(Duloxetine hydrochloride, NCI Thesaurus)
It exerts trophic action on retinal, cholinergic, and dopaminergic neurons in the brain and on motor and sensory neurons in the peripheral nervous system.
(Brain-Derived Neurotrophic Factor, NCI Thesaurus)
Inhibition of acetylcholinesterase is also used therapeutically to treat Alzheimer's disease, compensating for the loss of cholinergic neurons.
(Attenuation of GPCR Signaling Pathway, NCI Thesaurus/BIOCARTA)
Amoxapine also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which accounts for many of the side effects seen with this agent.
(Amoxapine, NCI Thesaurus)
