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CHRONIC LYMPHOCYTIC LEUKEMIA
Pronunciation (US): | (GB): |
I. (noun)
Sense 1
Meaning:
Chronic leukemia characterized by lymphoblast-like cells; more common in older men
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("chronic lymphocytic leukemia" is a kind of...):
chronic leukemia (slowly progressing leukemia)
Context examples:
This gene is involved in the regulation of gene expression and plays a role in the development of hepatocellular carcinoma and chronic lymphocytic leukemia.
(MIR16-2 Gene, NCI Thesaurus)
Alteration in the expression of this gene is associated with the development of both hepatocellular carcinoma and chronic lymphocytic leukemia.
(MIR16-2 wt Allele, NCI Thesaurus)
B-cell NHLs include Burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diffuse large B-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor B-lymphoblastic lymphoma, and mantle cell lymphoma.
(NHL, NCI Dictionary)
B-cell non-Hodgkin lymphomas include Burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diffuse large B-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor B-lymphoblastic lymphoma, and mantle cell lymphoma.
(non-Hodgkin lymphoma, NCI Dictionary)
GX015-070 is a selective antagonist of the BH3-binding groove of the Bcl-2 family proteins, which are frequently overexpressed in cancers including chronic lymphocytic leukemia (CLL).
(Obatoclax, NCI Thesaurus)
A regimen consisting of pentostatin and cyclophosphamide used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL).
(PC regimen, NCI Thesaurus)
Most patients present with slowly progressive chronic lymphocytic leukemia (CLL).
(Mu Heavy Chain Disease, NCI Thesaurus)
A monoclonal expansion of B-lymphocytes with or without the characteristic immunophenotype of chronic lymphocytic leukemia.
(monoclonal B-cell lymphocytosis, NCI Thesaurus)
This gene is involved in the regulation of gene expression and plays a role in the development of glioma, plasma cell myeloma and chronic lymphocytic leukemia.
(MIR181B1 Gene, NCI Thesaurus)
Alteration in the expression of this gene is associated with development of glioma, multiple myeloma and chronic lymphocytic leukemia.
(MIR181B1 wt Allele, NCI Thesaurus)