| Health / Medical Topics |
Cilazapril Anhydrous
The anhydrous form of the pyridazine angiotensin-converting enzyme (ACE) inhibitor cilazapril with antihypertensive activity. As a prodrug cilazapril is rapidly metabolized in the liver to cilazaprilat; cilazaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II, resulting in vasodilation. Cilazaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human CIITA wild-type allele is located in the vicinity of 16p13 and is approximately 48 kb in length. This allele, which encodes…
This gene plays a role in transcriptional regulation.
An agent belonging to the glitazone (thiazolidinedione) class of antidiabetic agents with antihyperglycemic activity. Ciglitazone also exerts anti-inflammatory activity through the modulation…
A small cigar similar in size to a cigarette. Unlike a cigarette, a cigarillo is wrapped in whole-leaf tobacco.
Inhaling smoke from tobacco in the form of a cigarette.
An individual who currently, or recently, smokes cigarettes regularly.
