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CIRRHOSIS
Pronunciation (US): | (GB): |
I. (noun)
Sense 1
Meaning:
A chronic disease interfering with the normal functioning of the liver; the major cause is chronic alcoholism
Synonyms:
cirrhosis; cirrhosis of the liver
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("cirrhosis" is a kind of...):
liver disease (a disease affecting the liver)
Context examples:
Although many patients who are infected with HBV may not have symptoms, long-term infection may lead to cirrhosis (scarring of the liver) and liver cancer.
(HBV, NCI Dictionary)
Other causes include immune disorders, genetic syndromes, and cirrhosis.
(Glucose Intolerance, NCI Thesaurus)
It may lead to cirrhosis and liver failure.
(Nonalcoholic Steatohepatitis, NCI Thesaurus)
Observed in 35% to 100% of patients with hepatocellular carcinoma, high serum ferritin levels may be due to ferritin production by the tumor cells, or related to the associated iron overload and/or cirrhosis.
(I 131 Antiferritin Immunoglobulin, NCI Thesaurus)
This can cause bile to build up in the liver, which may lead to cirrhosis (scarring of the liver) and liver damage.
(Alagille syndrome, NCI Dictionary)
NOS2A gene expression is up-regulated in liver cirrhosis and contributes to the progression of this disease state.
(NOS2 wt Allele, NCI Thesaurus)
The hepatitis C virus (HCV) causes liver inflammation and often leads to serious complications such as cirrhosis.
(Allergy drug inhibits hepatitis C, NIH)
A newly-discovered molecular mechanism that allows damaged adult liver cells to regenerate could pave the way for drugs to treat conditions such as cirrhosis or other chronic liver diseases where regeneration is impaired.
(Regeneration mechanism discovered in mice could provide target for drugs to combat chronic liver disease, University of Cambridge)
Marked fibrosis with cirrhosis is present.
(Ishak Score 6, NCI Thesaurus)
A syndrome characterized by progressive kidney failure in a patient with cirrhosis or fulminant liver failure.
(Hepatorenal Syndrome, NCI Thesaurus)