Health / Medical Topics |
Class II AP Endonuclease
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. (From LocusLink 27301) (NCI Thesaurus)
YOU MAY ALSO LIKE
Reconstruction of the occlusal surface of a tooth.
Class E basic helix-loop-helix protein 22 (381 aa, ~37 kDa) is encoded by the human BHLHE22 gene. This protein is involved in…
A type of analysis that determine the significance and/or magnitude of the difference between groups.
A sequence of characters that represents a particular category of items.
Gene expression profiling that classifies uveal melanomas into a high-grade group.
Uveal melanoma with intermediate metastatic risk as defined by gene expression profiling.