| Health / Medical Topics |
Clonal Regression
Definition 1
A biological process that selectively removes autoantigenic lymphocytes by targeting them for programmed cell death. (NCI Thesaurus)
Definition 2
Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion. (NLM, Medical Subject Headings)
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