Library / English Dictionary

CLOTTING FACTOR

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

Any of the factors in the blood whose actions are essential for blood coagulation

Synonyms:

clotting factor; coagulation factor

Classified under:

Nouns denoting substances

Hypernyms ("clotting factor" is a kind of...):

plasma protein (any of the proteins in blood plasma)

Hyponyms (each of the following is a kind of "clotting factor"):

factor I; fibrinogen (a protein present in blood plasma; converts to fibrin when blood clots)

factor II; prothrombin (a protein in blood plasma that is the inactive precursor of thrombin)

factor III; thrombokinase; thromboplastin (an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot)

calcium ion; factor IV (ion of calcium; a factor in the clotting of blood)

accelerator factor; factor V; proaccelerin; prothrombin accelerator (a coagulation factor)

cothromboplastin; factor VII; proconvertin; stable factor (a coagulation factor formed in the kidney under the influence of vitamin K)

antihaemophilic factor; antihaemophilic globulin; antihemophilic factor; antihemophilic globulin; factor VIII; Hemofil (a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A)

Christmas factor; factor IX (coagulation factor whose absence is associated with hemophilia B)

factor X; prothrombinase (coagulation factor that is converted to an enzyme that converts prothrombin to thrombin in a reaction that depends on calcium ions and other coagulation factors)

factor XI; plasma thromboplastin antecedent (coagulation factor whose deficiency results in a hemorrhagic tendency)

factor XII; Hageman factor (coagulation factor whose deficiency results in prolongation of clotting time of venous blood)

factor XIII; fibrinase (in the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot)

Credits

 Context examples: 

This prevents gamma carboxylation of glutamic acid residues near the N-terminals of the vitamin K-dependent clotting factors, including factor II, VII, IX, and X and anticoagulant proteins C and S. This prevents their activity and thus thrombin formation.

(Acenocoumarol, NCI Thesaurus)

Clotting factor is a protein needed for normal blood clotting.

(Hemophilia, NIH: National Heart, Lung, and Blood Institute)

For blood to clot, your body needs cells called platelets and proteins known as clotting factors.

(Bleeding Disorders, NIH)

If you have hemophilia, you have little or no clotting factor.

(Hemophilia, NIH: National Heart, Lung, and Blood Institute)