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COENZYME A
I. (noun)
Sense 1
Meaning:
A coenzyme present in all living cells; essential to metabolism of carbohydrates and fats and some amino acids
Classified under:
Hypernyms ("coenzyme A" is a kind of...):
coenzyme (a small molecule (not a protein but sometimes a vitamin) essential for the activity of some enzymes)
Context examples:
Water-soluble vitamin that is a component of coenzyme A and phosphopantetheine, which are involved in fatty acid metabolism.
(Pantothenic acid, NCI Thesaurus/CRCH)
A genetic disorder characterized by deficiency of the enzyme long-chain acyl-coenzyme A dehydrogenase that metabolizes long-chain fatty acids.
(Acyl-CoA Dehydrogenase, Long-Chain Deficiency, NCI Thesaurus)
An autosomal recessive inherited disorder characterized by a deficiency of the enzyme very long-chain acyl-coenzyme A dehydrogenase that metabolizes long-chain fatty acids.
(Acyl-CoA Dehydrogenase, Very Long-Chain Deficiency, NCI Thesaurus)
A genetic disorder characterized by deficiency of the enzyme short-chain acyl-coenzyme A dehydrogenase that metabolizes short-chain fatty acids.
(Acyl-CoA Dehydrogenase, Short-Chain Deficiency, NCI Thesaurus)
A genetic disorder characterized by deficiency of the enzyme medium-chain acyl-coenzyme A dehydrogenase that metabolizes medium-chain fatty acids.
(Acyl-CoA Dehydrogenase, Medium-Chain Deficiency, NCI Thesaurus)
This protein binds free fatty acids and their coenzyme a derivatives, bilirubin, and some other small molecules in the cytoplasm.
(Fatty Acid-Binding Protein 1, NCI Thesaurus)
Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine.
(Dexpanthenol, NCI Thesaurus)
The 1S isomer of crilvastatin, a pyrrolidone non-competitive inhibitor of hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase.
(Crilvastatin 1S, NCI Thesaurus)
Atorvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis.
(Atorvastatin, NCI Thesaurus)
Cerivastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis.
(Cerivastatin, NCI Thesaurus)
