Library / English Dictionary

COFACTOR

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A substance (as a coenzyme) that must join with another to produce a given result

Classified under:

Nouns denoting substances

Hypernyms ("cofactor" is a kind of...):

chemical compound; compound ((chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight)

Credits

 Context examples: 

Enzymes that metabolize NADH and NADPH are highly specific for one cofactor or the other and are in different pathways.

(Oxidative Reactions of the Pentose Phosphate Pathway, NCI Thesaurus/BIOCARTA)

Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis.

(Penicillamine, NCI Thesaurus)

This pathway illustrates two of the cofactor regulatory factors, MEF2 and PPARa, and an example orphan receptor feedback inhibition loop.

(PGC1a Regulation Pathway, NCI Thesaurus/BIOCARTA)

The protein, carbohydrates, fats and cofactors required to maintain a healthy body

(Nutritional Requirements, NCI Thesaurus)

Beta-catenin is a cytoskeletal component that enters the nucleus to act as a transcriptional cofactor.

(Notch and Wnt Signaling Pathway, NCI Thesaurus/BIOCARTA)

Proteins that include a metal ion as part of their structure or they contain a metal cofactor.

(Metalloprotein, NCI Thesaurus)

This agent also serves as a reducing cofactor with the hydroperoxidase moiety of cyclooxygenase and accelerates the conversion of arachidonic acid into precursors of PGI2.

(Nafazatrom, NCI Thesaurus)

Glutathione is also important as a cofactor for the enzyme glutathione peroxidase, in the uptake of amino acids, and in the synthesis of leukotrienes.

(Glutathione, NCI Thesaurus)

Studies of the role of biological agents as factors or cofactors in the etiology of human and animal cancer.

(Biological Carcinogenesis, NCI Thesaurus)

This protein is involved in biosynthesis of the molybdenum cofactor.

(Gephyrin, NCI Thesaurus)