Health / Medical Topics |
Colony-Stimulating Factor Gene
Colony-Stimulating Factor Genes encode Colony-Stimulating Factors, autocrine or paracrine glycoprotein growth factors that act synergistically on several bone marrow progenitor cells to regulate myeloid differentiation and stimulate production of blood cells. (NCI Thesaurus)
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A substance that stimulates the production of blood cells. Colony-stimulating factors include granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), and…
A functional (qualitative) as well as quantitative assay that is utilized as an indicator of granulopoiesis reconstitution.
A population of adherent cells in bone marrow cultures that resemble fibroblasts.
Any physiologic process which occurs in response to ligation of a colony stimulating factor receptor with a cognate ligand, and results in…
Any process which promotes expression of colony stimulating factors, their subsequent secretion, binding to their cognate receptors or intracellular signaling, and results…
A group of proteins found on the surface of hematopoietic cells that bind to colony stimulating factors and other ligands to regulate…