Health / Medical Topics

    COMMD1 wt Allele

    Human COMMD1 wild-type allele is located in the vicinity of 2p15 and is approximately 388 kb in length. This allele, which encodes COMM domain-containing protein 1, plays a role in the modulation of NF-kappa-B signaling, copper homeostasis and sodium uptake. The gene is aberrantly expressed in many tumors. (NCI Thesaurus)




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