Complement Component Gene

These genes encode more than 30 proteins of the complement system engaged in host defense. This system provides both an independent immune system capable of attacking microbes as well as other foreign material and an adjunct to the antibody system. Once activated, the complement system fires in a cascade-like fashion in which one component activates the next. Both swift and powerful, millions of complement components can deposit on an invading microbe within only a few minutes. Such a potent system requires strict regulation to avoid host injury. Membrane cofactor protein (MCP) is one critical regulator aimed at controlling inadvertent complement activation on host cells and nearly every cell examined expresses MCP on its cell membrane. (NCI Thesaurus)

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Complement C5a Measurement

The determination of the amount of complement C5a present in a sample.

Complement C5

Complement C5 (1676 aa, ~188 kDa) is encoded by the human C5 gene. This protein is involved in complement-mediated immunity.

Complement C4a Measurement

The determination of the amount of complement C4a present in a sample.

Complement C4 Measurement

The determination of the amount of complement C4 present in a sample.

Complement C3b Measurement

The determination of the amount of complement C3b present in a sample.

Complement C3a Measurement

The determination of the amount of complement C3a present in a sample.