Health / Medical Topics |
Congenic Strain
Congenic strains are produced by transferring a mutation from one genetic background to a specific inbred strain through repeated backcrossing. The congenic strain and the inbred partner are expected to be identical at all loci except for the transferred locus and a linked segment of chromosome. The size of the segment and the possibility of transferred alleles on other chromosomes depend on the number of backcross generations. A strain is considered fully congenic after ten generations of backcrossing (N10). (from JAX Strain Information) (NCI Thesaurus)
YOU MAY ALSO LIKE
A mental state in which one is not thinking clearly.
Issue associated with users being unclear and not able to follow any written, printed, or graphic matter that is affixed to a…
Polymorphism, single-stranded conformational, detection. Altered migration of single-stranded DNA molecules in non-denaturing gels based upon 3-D conformation. Uses PCR and/or restriction enzymes…
The three-dimensional arrangement of something in space. Often refers to the arrangement of the side groups on a molecule which can freely…
Correspondence in form or appearance.
A system of (usually) epifluorescence light microscopy in which a fine laser beam of light is scanned over the object through the…