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CONJUGATE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A mixture of two partially miscible liquids A and B produces two conjugate solutions: one of A in B and another of B in A
Synonyms:
Classified under:
Hypernyms ("conjugate" is a kind of...):
solution (a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution)
Derivation:
conjugate (unite chemically so that the product is easily broken down into the original compounds)
II. (adjective)
Sense 1
Meaning:
Of an organic compound; containing two or more double bonds each separated from the other by a single bond
Synonyms:
conjugate; conjugated
Classified under:
Similar:
bound (held with another element, substance or material in chemical or physical union)
Domain category:
chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)
Sense 2
Meaning:
Formed by the union of two compounds
Example:
a conjugated protein
Synonyms:
conjugate; conjugated
Classified under:
Similar:
bound (held with another element, substance or material in chemical or physical union)
Domain category:
chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)
Sense 3
Meaning:
(of a pinnate leaflet) having only one pair of leaflets
Classified under:
Adjectives
Similar:
compound (composed of more than one part)
Sense 4
Meaning:
Joined together especially in a pair or pairs
Synonyms:
conjugate; conjugated; coupled
Classified under:
Adjectives
Similar:
united (characterized by unity; being or joined into a single entity)
III. (verb)
Verb forms
Present simple: I / you / we / they conjugate ... he / she / it conjugates
Past simple: conjugated
Past participle: conjugated
-ing form: conjugating
Sense 1
Meaning:
Unite chemically so that the product is easily broken down into the original compounds
Classified under:
Verbs of size, temperature change, intensifying, etc.
Hypernyms (to "conjugate" is one way to...):
blend; coalesce; combine; commingle; conflate; flux; fuse; immix; meld; merge; mix (mix together different elements)
Domain category:
chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)
Sentence frame:
Somebody ----s something
Derivation:
conjugate (a mixture of two partially miscible liquids A and B produces two conjugate solutions: one of A in B and another of B in A)
Sense 2
Meaning:
Undergo conjugation
Classified under:
Verbs of size, temperature change, intensifying, etc.
Hypernyms (to "conjugate" is one way to...):
change (undergo a change; become different in essence; losing one's or its original nature)
Domain category:
biological science; biology (the science that studies living organisms)
Sentence frame:
Something ----s
Derivation:
conjugation (the act of pairing a male and female for reproductive purposes)
Sense 3
Meaning:
Add inflections showing person, number, gender, tense, aspect, etc.
Example:
conjugate the verb
Classified under:
Verbs of telling, asking, ordering, singing
Hypernyms (to "conjugate" is one way to...):
inflect (change the form of a word in accordance as required by the grammatical rules of the language)
Sentence frame:
Somebody ----s something
Derivation:
conjugation (a class of verbs having the same inflectional forms)
conjugation (the complete set of inflected forms of a verb)
conjugation (the inflection of verbs)
Context examples:
An immunoconjugate consisting of milatuzumab, a humanized monoclonal antibody against CD74, conjugated to the anthracycline antibiotic doxorubicin with potential antineoplastic activity.
(Milatuzumab-Doxorubicin Antibody-Drug Conjugate, NCI Thesaurus)
This agent may be conjugated with various toxins in order to target their cytotoxic activity to tumor cells expressing the L6 antigen.
(Monoclonal Antibody L6, NCI Thesaurus)
When conjugated with a radioactive isotope, Lym-1 monoclonal antibody selectively transports the cytotoxic radioisotope to HLA-Dr10-expressing tumor cells, thereby sparing healthy B-cells and normal tissues.
(Monoclonal Antibody Lym-1, NCI Thesaurus)
A peptide vaccine containing the human tumor-associated antigen epithelial mucin (MUC1 antigen) conjugated with keyhole limpet hemocyanin (KLH) and combined with the nonspecific immunoadjuvant QS21, with potential antineoplastic activity.
(MUC1-KLH Vaccine/QS21, NCI Thesaurus)
An immunotoxin consisting of a murine monoclonal antibody (MCA) conjugated to the toxin ricin.
(Murine MCA Ricin Conjugate, NCI Thesaurus)
A vaccine consisting of myeloma-specific immunoglobulin conjugated to keyhole limpet hemocyanin (KLH), an immune stimulant, with potential antineoplastic activity.
(Myeloma Ig Id-KLH Conjugate Vaccine, NCI Thesaurus)
In this vaccine, MUC1 antigen is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition.
(MUC1-KLH Conjugate Vaccine, NCI Thesaurus)
It may be conjugated with a radioactive element and used in radioimmunotherapy (RIT), a procedure that uses a tumor-specific monoclonal antibody to target radiation to cancer cells.
(Monoclonal Antibody m170, NCI Thesaurus)
A peptide vaccine containing human mucin 2 (MUC2) protein conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity.
(MUC-2-KLH Vaccine, NCI Thesaurus)
The monoclonal antibody component recognizes and attaches to the membrane-associated antigen, dopamine-b-hydroxylase, resulting in the conjugate being internalized by receptor-mediated endocytosis.
(Anti-Dopamine-b-Hydroxylase Monoclonal Antibody-Saporin, NCI Thesaurus)
