| Health / Medical Topics |
Connector Enhancer of KSR-Like Protein
Connector Enhancer of KSR-Like (Drosophila Kinase Suppressor of Ras) is encoded by the human CNK1 gene. Drosophila CNK is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway. Drosophila CNK interacts with RAF and localizes to cell junctions, required by several pathways stimulated by receptor tyrosine kinases. The function, location or structure of human CNK1 remains unknown. (From OMIM and NCI) (NCI Thesaurus)
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