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CONTRACTILITY
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The capability or quality of shrinking or contracting, especially by muscle fibers and even some other forms of living matter
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("contractility" is a kind of...):
ability (the quality of being able to perform; a quality that permits or facilitates achievement or accomplishment)
Hyponyms (each of the following is a kind of "contractility"):
astringency; stypsis (the ability to contract or draw together soft body tissues to check blood flow or restrict secretion of fluids)
Derivation:
contractile (capable of contracting or being contracted)
Context examples:
Diltiazem inhibits the transmembrane influx of extracellular calcium ions into select myocardial and vascular smooth muscle cells, causing dilatation of coronary and systemic arteries and decreasing myocardial contractility.
(Diltiazem Malate, NCI Thesaurus)
Felodipine inhibits the influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility.
(Felodipine, NCI Thesaurus)
Betaxolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate.
(Betaxolol, NCI Thesaurus)
This allele, which encodes sarcoplasmic/endoplasmic reticulum calcium ATPase 2 protein, is involved in the modulation of cardiac muscle contractility.
(ATP2A2 wt Allele, NCI Thesaurus)
Furthermore, decreased myocardial contractility and dilation of the main coronary and systemic arteries lead to increased blood flow and oxygen delivery to the myocardial tissue and decreases total peripheral resistance.
(Amlodipine Maleate, NCI Thesaurus)
This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance.
(Amlodipine, NCI Thesaurus)
Diltiazem hydrochloride inhibits the transmembrane influx of extracellular calcium ions into select myocardial and vascular smooth muscle cells, causing dilatation of coronary and systemic arteries and decreasing myocardial contractility.
(Diltiazem Hydrochloride, NCI Thesaurus)
Bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate.
(Bisoprolol, NCI Thesaurus)
Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility.
(Digoxin, NCI Thesaurus)
Devoid of intrinsic sympathomimetic activity, bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, decreasing cardiac contractility and rate, reducing cardiac output, and lowering blood pressure.
(Bisoprolol Fumarate, NCI Thesaurus)
