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    Corticorelin Ovine Triflutate

    A trifluoroacetate salt of ovine corticotropin-releasing hormone (CRH), a 41 amino acids peptide similar to human CRH, used as a diagnostic agent. Corticorelin ovine triflutate is a potent stimulator of adrenocorticotropic hormone (ACTH), secreted from the anterior pituitary gland. In turn, ACTH stimulates cortisol production from the adrenal cortex and is regulated by a negative feedback mechanism. Corticorelin ovine triflutate is used as a diagnostic tool in differentiating pituitary and ectopic production of ACTH. (NCI Thesaurus)




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