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    CpG Island Methylator Phenotype

    A phenotype whereby a subset of tumors are characterized by the simultaneous hypermethylation of multiple promoter-associated CpG islands. (NCI Thesaurus)




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    Short region of DNA in which the frequency of the CG sequence is higher than in other regions.
    A dinucleotide consisting of cytosine followed by guanine.
    Any immunoglobulin that recognizes cytosine/guanine (CpG) rich sequences in chromosomal DNA.
    A substance that is being studied in the treatment of some types of cancer. It belongs to the family of drugs called…
    Human CPE wild-type allele is located in the vicinity of 4q32.3 and is approximately 120 kb in length. This allele, which encodes…
    A protein encoded by the CPE gene.

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