Health / Medical Topics

    CRBN wt Allele

    Human CRBN wild-type allele is located in the vicinity of 3p26.3 and is approximately 31 kb in length. This allele, which encodes protein cereblon protein, is involved in ubiquitin-mediated protein degradation. Mutations are associated with autosomal recessive nonsyndromic mental retardation. (NCI Thesaurus)




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