Health / Medical Topics

    CRKL wt Allele

    Human CRKL wild-type allele is located in the vicinity of 22q11.21 and is approximately 36 kb in length. This allele, which encodes Crk-like protein, is involved in signal transduction. The CRKL gene is overexpressed in certain types of cancer such as breast, colon, lung, ovarian and skin cancer. (NCI Thesaurus)




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