CRTC1/MAML2 Fusion Protein

A fusion protein (1024 aa, ~112 kDa) encoded by the CRTC1/MAML2 fusion gene. This protein is comprised of the first 42 N-terminal amino acids of the CREB-regulated transcription coactivator 1 protein fused to most of the mastermind-like protein 2. (NCI Thesaurus)

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CRTC1/MAML2 Fusion Gene

A fusion gene (~3.8 kb) that results from a chromosomal translocation t(11;19)(q14-q21;p13-p12) which fuses exon 1 of the CRTC1 gene to exons…

CRTC1 wt Allele

Human CRTC1 wild-type allele is located in the vicinity of 19p13.11 and is approximately 99 kb in length. This allele, which encodes…

CRTC1 Gene

This gene plays a role in the positive regulation of transcription.

CRTAM wt Allele

Human CRTAM wild-type allele is located in the vicinity of 11q24.1 and is approximately 34 kb in length. This allele, which encodes…

CRTAM Gene

This gene is involved in immune function.

CRPC

Prostate cancer that keeps growing even when the amount of testosterone in the body is reduced to very low levels. Many…