Health / Medical Topics

    CST3 wt Allele

    Human CST3 wild-type allele is located in the vicinity of 20p11.21 and is approximately 4 kb in length. This allele, which encodes cystatin-C protein, plays a role in the regulation of cysteine protease activity. Mutation of the gene is associated with both amyloidosis type 6 and age-related macular degeneration type 11. (NCI Thesaurus)




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