CTCAE Grade 1 Irritability in Children Less Than 3 Years of Age

Mild; easily consolable (NCI Thesaurus/CTCAE)

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CTCAE Grade 1 Irregular Menses

1 - 3 months without menses

CTCAE Grade 1 Intestine Pain

Mild pain not interfering with function

CTCAE Grade 1 International Normalized Ratio of Prothrombin Time

1 - 1.5 x ULN

CTCAE Grade 1 Insomnia

Occasional difficulty sleeping, not interfering with function

CTCAE Grade 1 Inner Ear Intra-Operative Injury

Primary repair of injured organ/structure indicated

CTCAE Grade 1 Injection Site Reaction or Extravasation Changes

Pain; itching; erythema