CTCAE Grade 1 Tumor Flare

Asymptomatic, weakness on physical exam

Decreased range of motion without impaired eating

Asymptomatic, no intervention indicated

Mild and brief or intermittent but not interfering with function

Asymptomatic obstruction or stenosis on exam, endoscopy, or radiograph

Upper aerodigestive tract sites: Minimal symptoms, normal diet; minimal respiratory symptoms but not interfering with function Lower GI sites: Minimal discomfort, intervention…