CTCAE Grade 2 Anal Sphincter Intra-Operative Injury

Partial resection of injured organ/structure indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Anal or Perianal Infection with Unknown Absolute Neutrophil Count

Localized, local intervention indicated

CTCAE Grade 2 Anal or Perianal Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

Localized, local intervention indicated

CTCAE Grade 2 Anal or Perianal Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils

Localized, local intervention indicated

CTCAE Grade 2 Anal Incontinence

Daily use of pads required

CTCAE Grade 2 Amylase

1.5 - 2.0 x ULN

CTCAE Grade 2 Alteration in Bone Age

+/-2 SD (standard deviation) from normal