CTCAE Grade 2 Edema of the Limb

10 - 30% inter-limb discrepancy in volume or circumference at point of greatest visible difference; readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Edema of the Head and Neck

Localized facial or neck edema with functional impairment

CTCAE Grade 2 Dyspnea

Dyspnea on exertion but unable to walk 1 flight of stairs or 1 city block (0.1km) without stopping

CTCAE Grade 2 Dysphagia

Symptomatic and altered eating/swallowing (e.g., altered dietary habits, oral supplements); IV fluids indicated <24 hrs

CTCAE Grade 2 Duodenum Ulcer

Symptomatic; altered GI function (e.g., altered dietary habits, oral supplements); IV fluids indicated <24 hrs

CTCAE Grade 2 Duodenum Stricture or Stenosis

Symptomatic; altered GI function (e.g., altered dietary habits, vomiting, bleeding, diarrhea); IV fluids indicated <24 hrs

CTCAE Grade 2 Duodenum Perforation

Medical intervention indicated; IV fluids indicated <24 hrs