CTCAE Grade 2 Esophagus Fistula

Symptomatic; altered GI function (e.g., altered dietary habits, diarrhea, or GI fluid loss); IV fluids indicated <24 hrs (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Esophagitis

Symptomatic; altered eating/swallowing (e.g., altered dietary habits, oral supplements); IV fluids indicated <24 hrs

CTCAE Grade 2 Esophageal Varices Hemorrhage

Symptomatic and medical intervention or minor cauterization indicated

CTCAE Grade 2 Erectile Dysfunction

Decrease in erectile function (frequency/rigidity of erections), erectile aids indicated

CTCAE Grade 2 Epiphora

Symptomatic, interfering with function but not interfering with ADL

CTCAE Grade 2 Enteritis

Abdominal pain; mucus or blood in stool

CTCAE Grade 2 Encephalopathy

Mild signs or symptoms; not interfering with ADL