CTCAE Grade 2 Extrapyramidal and Involuntary Movement and Restlessness

Moderate involuntary movements interfering with function, but not interfering with ADL (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Extraocular Muscle Weakness Not Due to Neuropathy

Symptomatic and interfering with function, but not interfering with ADL

CTCAE Grade 2 External Ear Pain

Moderate pain; pain or analgesics interfering with function, but not interfering with ADL

CTCAE Grade 2 External Ear Infection with Unknown Absolute Neutrophil Count

Localized, local intervention indicated

CTCAE Grade 2 External Ear Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

Localized, local intervention indicated

CTCAE Grade 2 External Ear Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils

Localized, local intervention indicated

CTCAE Grade 2 Exostosis

Involving multiple sites; pain or interfering with function