CTCAE Grade 2 Fibrosis-Cosmesis

<0.75 - 0.5 x LLN or 25 - <50% decrease from baseline

39.0 - 40.0 degrees C (102.3 - 104.0 degrees F)

<75 - 50% of predicted value

Symptomatic; noninvasive intervention indicated

Moderate or causing difficulty performing some ADL

Symptomatic but no hydronephrosis, sepsis or renal dysfunction; dilation or endoscopic repair or stent placement indicated