CTCAE Grade 2 Induration or Fibrosis of the Skin and Subcutaneous Tissue

Moderate impairment of function not interfering with ADL; marked increase in density and firmness on palpation with or without minimal retraction (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Ileus

Symptomatic; altered GI function (e.g., altered dietary habits); IV fluids indicated <24 hrs

CTCAE Grade 2 Ileum Ulcer

Symptomatic; altered GI function (e.g., altered dietary habits, oral supplements); IV fluids indicated <24 hrs

CTCAE Grade 2 Ileum Stricture or Stenosis

Symptomatic; altered GI function (e.g., altered dietary habits, vomiting, bleeding, diarrhea); IV fluids indicated <24 hrs

CTCAE Grade 2 Ileum Perforation

Medical intervention indicated; IV fluids indicated <24 hrs

CTCAE Grade 2 Ileum Obstruction

Symptomatic; altered GI function (e.g., altered dietary habits, vomiting, diarrhea, or GI fluid loss); IV fluids indicated <24 hrs

CTCAE Grade 2 Ileum Intra-Operative Injury

Partial resection of injured organ/structure indicated