CTCAE Grade 2 International Normalized Ratio of Prothrombin Time

1.5 - 2 x ULN (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Insomnia

Difficulty sleeping, interfering with function but not interfering with ADL

CTCAE Grade 2 Inner Ear Intra-Operative Injury

Partial resection of injured organ/structure indicated

CTCAE Grade 2 Injection Site Reaction or Extravasation Changes

Pain or swelling, with inflammation or phlebitis

CTCAE Grade 2 Infertility and Sterility

Male: oligospermia/low sperm count Female: diminished fertility/ovulation

CTCAE Grade 2 Inferior Vena Cava Vein Injury

Symptomatic (e.g., claudication); not interfering with ADL; repair or revision not indicated

CTCAE Grade 2 Inferior Vena Cava Intra-Operative Injury

Partial resection of injured organ/structure indicated