CTCAE Grade 2 Jejunum Fistula

Symptomatic; altered GI function (e.g., altered dietary habits, diarrhea, or GI fluid loss); IV fluids indicated <24 hrs (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Irritability in Children Less Than 3 Years of Age

Moderate; requiring increased attention

CTCAE Grade 2 Irregular Menses

3 - 6 months without menses but continuing menstrual cycles

CTCAE Grade 2 Iron Overload

Asymptomatic iron overload, intervention not indicated

CTCAE Grade 2 Intestine Pain

Moderate pain; pain or analgesics interfering with function, but not interfering with ADL

CTCAE Grade 2 International Normalized Ratio of Prothrombin Time

1.5 - 2 x ULN

CTCAE Grade 2 Insomnia

Difficulty sleeping, interfering with function but not interfering with ADL