CTCAE Grade 2 Non-Septic Arthritis

Moderate pain with inflammation, erythema, or joint swelling interfering with function, but not interfering with ADL (NCI Thesaurus/CTCAE)

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CTCAE Grade 2 Non-Myocardial Visceral Arterial Ischemia

Brief (<24 hrs) episode of ischemia managed medically and without permanent deficit

CTCAE Grade 2 Non-Malignant Pleural Effusion

Symptomatic, intervention such as diuretics or up to 2 therapeutic thoracenteses indicated

CTCAE Grade 2 Non-Malignant Ascites

Symptomatic, medical intervention indicated

CTCAE Grade 2 Non-Infectious Wound Complication

Incisional separation >25% of wound with local care; asymptomatic hernia

CTCAE Grade 2 Non-Infectious Vaginal Discharge

Moderate to heavy; pad use indicated

CTCAE Grade 2 Nodal or Junctional Rhythm

Non-urgent medical intervention indicated